Ziyan Zhuang | I love biology — more is different.

Ziyan Zhuang

I am an undergraduate researcher in Biological Science at Xinjiang University. My research explores the intersection of Life Sciences and Computational Design (AI for Science).

I love biology — more is different.

My academic journey includes enriching experiences at Shanghai Jiao Tong University and Peking University through summer programs.

Research Interest: Synthetic Biology, Protein Language Models, and AI Agents for Science.

I am actively seeking academic collaborations, particularly in AI for Science, Computer Science (CS), and Quantum Mechanics (QM). Please feel free to contact me via email.

Email: Zhuangziyan0623@outlook.com
Location: Urumqi, China (To Jun, 2026)

Email / CV / Github / ORCID / Google Scholar

News & Honors

[08/2025] Attended Summer School at Shanghai Jiao Tong University (AI for Bioengineering), Institute of Natural Sciences. Thanks SJTU!
[08/2024] Received Second Prize at China Undergraduate Life Sciences Contest (National, TEAM LEADER).
[08/2024] Received Outstanding Newcomer Award from The Chinese Society of Biochemistry and Molecular Biology.
[07/2024] Attended Summer School at Peking University (Quantitative Biology), Center for Life Science (CLS). Thanks ♥ PKU
[2023–2024] Project Leader for National Training Program of Innovation (CNY 20,000 Grant). Thanks XJU!
[2023–2024] Joint Minor: Climate Change and Carbon Neutrality, College of Environmental Science and Engineering, Tongji University & Xinjiang University. Thanks TJU&XJU!
[06/2024] Participated in field research (Wildlife Monitoring) in the Northern Tianshan Mountains. Thank you Dr. Zhong.

Selected Publications

* denotes corresponding author.

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Spinetoram resistance in Tuta absoluta: selection, inheritance, biochemical mechanism and fitness cost
Xie JG, Rukiya T, Liu N, Zhuang ZY, Liu XN*, Song Y*.
Pesticide Biochemistry and Physiology, 2025 JCR Q1
Paper

Molecular insights on the function of CYP380C12 in Aphis gossypii Glover (Hemiptera: Aphididae): in silico and RNAi analyses
Zhang LJ, Zhuang ZY (Co-first), Xie JG, Kong WT, Li TT, Wang SF, Liu XN*.
Journal of Economic Entomology, 2025 JCR Q1
Paper

Functional analysis of lactase phlorizin hydrolase in insect-plant coevolution based on deglycosylation
Li Y, Kong WT, Li TT, Zhang LJ, Zhuang ZY, Liu N*, Liu XN*.
Journal of Agricultural and Food Chemistry, Cover Paper, 2025 JCR Q1
Paper

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Exploring the role of CYP6AB328 in spinetoram resistance and growth and development of Phthorimaea absoluta
Xie JG, Wang SY, Zhuang ZY, Wang XH, Lin MH, Liu XN*.
Pesticide Biochemistry and Physiology, 2025 JCR Q1
Paper

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Functional Investigation of CYP304F1 in Tuta absoluta (Lepidopteran: Gelechiidae) by RNA Interference
Xie JG, Ali A, Li Y, Zhuang ZY, Liu XN*.
Journal of Economic Entomology, 2024 JCR Q1
Paper

Projects & Software

ProXplorer: A Protein Sequence Analysis Toolbox
Ziyan Zhuang
GitHub

A MATLAB-based toolbox developed for comprehensive protein sequence analysis. Key features include Smith-Waterman alignment, motif discovery, and neighbor-joining phylogenetic analysis. It provides integrated visualization to streamline the workflow from raw sequence to structural insights.

Morphogen-DAU-Model
Ziyan Zhuang & Zifan Zhao
GitHub

A mathematical model focusing on Diffusion-Adsorption-Uptake (DAU) mechanisms. This project facilitates the efficient application of predictive values obtained from wet lab experiments to control morphogen distribution patterns.

Deep Learning

BOGDA: Pest Resistance Evolution Models
Ziyan Zhuang, Qi-ao Sheng, et al.
GitHub

A Deep Learning framework utilizing Temporal Convolutional Networks (TCN) and Attention mechanisms to predict pest resistance evolution, bridging mathematical models with biological pest control strategies.

Field Practice & Academic Programs

Wildlife Monitoring Footage from Field Practice (GIF)

Wildlife Monitoring Field Practice (Northern Tianshan Mountains)
June 2024
Ziyan Zhuang, Zifan Zhao, et al.

Participated in field research in the Northern Tianshan Mountains, using infrared camera technology to record and analyze the behavior and distribution of local wild animals. The visual above shows representative footage captured during the internship.

Shanghai Jiao Tong University Summer School

AI for Bioengineering Summer School (Shanghai Jiao Tong University)
August 2025

Participated in the summer school at the Institute of Natural Sciences, Shanghai Jiao Tong University, focusing on the application of artificial intelligence in bioengineering. Learned cutting-edge techniques including AI-driven protein design and computational biology workflows.

Quantitative Biology Summer School (Peking University)
July 2024

Participated in the summer school at the Center for Life Science (CLS), Peking University, exploring quantitative methods in biological research, including mathematical modeling of biological systems and data-driven experimental design.